Stability and structural reversibility of proteins exposed to high temperatures

Thermal stability of proteins During various industrial processes it is necessary for proteins to be temporarily placed under elevated temperatures. It is crucial to understand whether the protein of importance is stable at increased temperatures and whether the effects of increasing the temperature are reversible. The resistance of a protein to denaturation and its ability to refold are also modulated by the chemical conditions under which this process occurs. Therefore, it is advantageous for the design of industrially useful heat-resistant proteins to have a multi-sample platform on which protein thermal denaturation and refolding can be assessed.